Company Filing History:
Years Active: 2010-2022
Title: Innovations by Inventor Jeung-Hoi Ha
Introduction
Jeung-Hoi Ha, an accomplished inventor located in Manlius, NY, has made significant contributions to the field of biotechnology. With a total of four patents to his name, his work primarily focuses on enhancing the solubility and expression of proteins, which is vital in various scientific and medical applications.
Latest Patents
One of Ha's latest patents is titled "Compositions and methods comprising permuted protein tags for facilitating overexpression, solubility, and purification of target proteins." This patent provides methods and compositions that aid in solubilizing, stabilizing, and expressing proteins, specifically fusion proteins containing a protein of interest. The innovative approach involves the use of segments from Ribose Binding Protein (RBP) or Maltose Binding Protein (MBP) to enhance the characteristics of the target protein. These segments can be positioned in different orientations relative to the target protein, potentially improving both expression and solubility.
Another notable patent is the "Cleavable fusion tag for protein overexpression and purification," which centers around improving recombinant protein production. By utilizing the Ribose Binding Protein as part of a fusion polypeptide, this method enhances the yield of the fusion protein. The innovations also include recombinant expression vectors and methods for separating fusion proteins, facilitating better recovery of the desired polypeptide.
Career Highlights
Ha's career is marked by his tenure at the State University of New York, where he has been instrumental in advancing research in protein expression technology. His innovative methodologies have the potential to transform practices in protein analysis and pharmaceutical development.
Collaborations
Throughout his career, Jeung-Hoi Ha has collaborated with prominent colleagues, including Stewart N. Loh and Adam R. Blanden. These collaborations underscore the synergy between researchers in the field and highlight the importance of teamwork in driving innovation.
Conclusion
Jeung-Hoi Ha's remarkable contributions to biotechnology through his patented innovations reflect his commitment to enhancing protein science. As his work continues to evolve, it paves the way for future advancements in medical research and therapeutic applications.