Company Filing History:
Years Active: 1995
Title: Jerome Salem: Innovator in Antimalarial Research
Introduction
Jerome Salem is a notable inventor based in Cheltenham, PA (US). He has made significant contributions to the field of antimalarial research, particularly through his innovative work on the ribonucleotide reductase of Plasmodium falciparum.
Latest Patents
Jerome Salem holds a patent for his invention titled "Plasmodium falciparum ribonucleotide reductase DNA." This invention focuses on the ribonucleotide reductase of Plasmodium falciparum (Pf RR) and its subunits, Pf R1 and Pf R2. The patent describes compounds comprising peptides derived from the Pf R2 C-terminus sequence that inhibit the action of protozoal RR. The invention provides methods for the prevention and treatment of malaria caused by P. falciparum by controlling its proliferation through the administration of at least one peptide. Additionally, antimalarial compositions are included, which consist of a pharmaceutically acceptable carrier and at least one peptide that inhibits the P. falciparum ribonucleotide reductase's reduction of ribonucleotides to 2'-deoxyribonucleotides. The patent also outlines methods for diagnosing malaria and screening potential antimalarial agents.
Career Highlights
Jerome Salem is affiliated with the University of Pennsylvania, where he continues to advance his research in the field of malaria treatment. His work has garnered attention for its potential impact on public health, particularly in regions affected by malaria.
Collaborations
Throughout his career, Jerome has collaborated with esteemed colleagues such as Barry S Cooperman and Harvey Rubin. These collaborations have further enriched his research and contributed to the development of innovative solutions in the fight against malaria.
Conclusion
Jerome Salem's contributions to antimalarial research through his patent on Plasmodium falciparum ribonucleotide reductase DNA highlight his commitment to addressing significant health challenges. His work exemplifies the importance of innovation in the field of medicine.