Company Filing History:
Years Active: 1987-1994
Title: Jere P Segrest: Innovator in Lipoprotein Analysis
Introduction
Jere P Segrest, an accomplished inventor based in Birmingham, Alabama, is renowned for his innovative contributions to the field of lipoprotein analysis. With a total of two patents to his name, Segrest's work focuses on advancing the understanding and measurement of cholesterol distribution in the bloodstream.
Latest Patents
One of Segrest's notable patents addresses the determination of lipoprotein concentration in blood through a controlled continuous flow analysis system. This cutting-edge method measures cholesterol distribution among different lipoprotein classes in a blood sample. The process begins with the separation of a blood plasma sample into distinct lipoprotein classes via single vertical spin density gradient ultracentrifugation. The separated sample is introduced into a continuous reagent stream, which flows through a detector. The system continuously monitors the reaction's absorbance, providing a transient signal that enables a relatively short reaction period. This absorbance data is then digitized and analyzed using computer technology to generate a cholesterol profile that indicates the concentration of cholesterol in each lipoprotein class.
Additionally, Segrest has developed an invention related to amphipathic peptides, which refers to peptides characterized by their dual affinity for both hydrophilic and hydrophobic environments. This innovation highlights his expertise in biochemistry and molecular biology.
Career Highlights
Throughout his career, Segrest has collaborated with well-regarded organizations, including Research Incorporated and the UAB Research Foundation. His work in these institutions has significantly contributed to advancements in lipid research and biomolecular analysis.
Collaborations
Segrest has worked alongside esteemed colleagues Gattadahalli M Anantharamaiah and Krishnaji R Kulkarni. Their collective efforts have furthered the exploration of lipoprotein biology and its implications for human health.
Conclusion
Jere P Segrest’s contributions to the field of lipoprotein analysis exemplify his dedication to advancing biomedical science. His innovative patents have paved the way for improved methods of cholesterol measurement, contributing to a deeper understanding of cardiovascular health.