Company Filing History:
Years Active: 2003-2019
Title: Jeong-Han Kim: Innovator in Osteogenesis and Adipocyte Differentiation
Introduction
Jeong-Han Kim is a prominent inventor based in Seoul, South Korea. He has made significant contributions to the fields of osteogenesis and adipocyte differentiation, holding a total of five patents. His innovative work focuses on the use of human small leucine zipper proteins in various biological processes.
Latest Patents
One of his latest patents is titled "Use of human small leucine zipper protein in osteogenesis procedure." This invention relates to the application of a human small leucine zipper protein in the osteogenesis procedure. Specifically, sLZIP increases the transcriptional activity of Runx2 and inhibits the transcriptional activity of PPARγ2, thereby enhancing osteoblast differentiation. This discovery positions sLZIP as a crucial marker for treating bone diseases and developing new medicines.
Another significant patent is "Use of human small leucine zipper protein in adipocyte differentiation procedure." This invention discusses the role of sLZIP in adipocyte differentiation. It binds with PPARγ2 to form a complex with HDAC3 and PPARγ2, functioning as a corepressor that negatively inhibits the transcriptional activity of PPARγ2. This mechanism suppresses differentiation into adipocytes, making it a potential marker for treating diabetes and obesity, as well as for developing new therapeutic approaches.
Career Highlights
Jeong-Han Kim has worked with notable institutions such as the Korea University Research and Business Foundation and the Korea Research Institute of Chemical Technology. His work in these organizations has allowed him to advance his research and contribute to significant scientific advancements.
Collaborations
Throughout his career, Jeong-Han Kim has collaborated with esteemed colleagues, including Je Sang Ko and Kwang-Yun Cho. These partnerships have fostered a collaborative environment that enhances innovation and research outcomes.
Conclusion
Jeong-Han Kim is a distinguished inventor whose work in osteogenesis and adipocyte differentiation has the potential to impact medical treatments significantly. His innovative patents and collaborations highlight his commitment to advancing scientific knowledge and improving health outcomes.