Company Filing History:
Years Active: 2018-2021
Title: Jens Wölfel: Innovator in Recombinant Glycoproteins
Introduction
Jens Wölfel is a notable inventor based in Langenfeld, Germany. He has made significant contributions to the field of biotechnology, particularly in the development of recombinant glycoproteins. With a total of 3 patents to his name, Wölfel's work focuses on enhancing the properties of glycoproteins for various applications.
Latest Patents
Wölfel's latest patents include innovative methods for producing recombinant glycoproteins with specific modifications. One of his patents, titled "Recombinant glycoproteins with reduced antennary fucosylation," describes methods for reducing antennary fucosylation of complex N-glycans in recombinantly expressed glycoproteins. This invention also details the cell lines that can be utilized in these methods, along with the respective recombinant glycoproteins and their expression techniques. Another significant patent is "O-glycan sialylated recombinant glycoproteins," which relates to genetically modified cell lines that overexpress a β-galactoside α-2,3-sialyltransferase 1 (ST3Gal1). This invention aims to produce recombinant glycoproteins with highly or fully sialylated O-linked GalNAc glycans, enhancing their functionality and reducing micro-heterogeneity.
Career Highlights
Throughout his career, Jens Wölfel has worked with prominent companies in the biotechnology sector, including Cevec Pharmaceuticals GmbH. His expertise in glycoprotein engineering has positioned him as a key player in the development of advanced biopharmaceuticals. His innovative approaches have contributed to the advancement of therapeutic proteins, making them more effective for clinical applications.
Collaborations
Wölfel has collaborated with several professionals in his field, including Silke Wissing and Nicole Faust. These collaborations have fostered a productive environment for research and development, leading to significant advancements in glycoprotein technology.
Conclusion
Jens Wölfel's contributions to the field of recombinant glycoproteins highlight his innovative spirit and dedication to advancing biotechnology. His patents and career achievements reflect a commitment to improving the efficacy of therapeutic proteins, making a lasting impact in the industry.