Company Filing History:
Years Active: 2001
Title: The Innovative Contributions of Jennifer L. Karas
Introduction
Jennifer L. Karas is a notable inventor based in Lexington, MA (US). She has made significant contributions to the field of biochemistry, particularly in the study of protein kinases. Her work has implications for the development of pharmaceutical compositions aimed at inhibiting specific biological functions.
Latest Patents
Jennifer holds a patent for a "Three dimensional structure of a ZAP tyrosine protein kinase fragment and modeling methods." This invention focuses on the human ZAP-70 protein, specifically the tandem Src homology-2 (SH2) domains. The patent describes crystalline forms of ZAP-70, both liganded and unliganded, which are essential for determining the three-dimensional structure of the protein. This structural information is crucial for designing pharmaceutical compositions that can inhibit the biological functions of ZAP and related proteins.
Career Highlights
Jennifer is currently associated with Ariad Pharmaceuticals, Inc., where she continues her research and development efforts. Her work has been instrumental in advancing the understanding of protein interactions and their implications in various biological processes.
Collaborations
Jennifer has collaborated with notable colleagues, including Marcos H. Hatada and Xiaode Lu. These collaborations have further enriched her research and contributed to the advancement of knowledge in her field.
Conclusion
Jennifer L. Karas exemplifies the innovative spirit of modern inventors. Her contributions to the understanding of protein structures and their biological functions are paving the way for new therapeutic approaches.