Jennifer E Grant

Title: Jennifer E. Grant: Inventor of a Modular Citrulline Detection Probe

Introduction

Jennifer E. Grant is an inventor associated with Menomonie, Wisconsin, and Wisys Technology Foundation, Inc. Her work includes a chemical probe designed to detect the amino acid citrulline in physiological samples. The available information identifies 1 patent associated with her.

Latest Patents

Grant’s listed patent is titled “Modular Chemical Probe for Detection of Amino Acid Citrulline in Physiological Samples.” The invention combines a reactive head made from a 1,3-dicarbonyl moiety with a modular approach to labeling citrulline side chains. The reactive head is designed to interact with citrulline more effectively than currently used 1,2-dicarbonyl moieties.

The probe first labels citrulline side chains, after which a separate read-out subunit or tag can be attached. Possible tags include a fluorophore, nanoparticle, or antigen. The modular design keeps the initial probe smaller, which may improve sensitivity, and allows the same sample to be analyzed using different read-out methods.

Career Highlights

Grant’s listed invention focuses on improving the detection and analysis of citrulline in physiological samples. Its modular design separates the chemical labeling step from the choice of detection tag, offering flexibility in how researchers examine a sample.

Collaborations

The provided information names Dmitry V. Kadnikov as Grant’s coworker. Grant is also associated with Wisys Technology Foundation, Inc.

Conclusion

Jennifer E. Grant’s listed patent presents a modular chemical probe intended to improve citrulline detection through a more reactive labeling component and flexible read-out options.