Company Filing History:
Years Active: 1998-2001
Title: Jennie B Nerenberg: Innovator in Pharmaceutical Chemistry
Introduction
Jennie B Nerenberg is a notable inventor based in Maple Glen, PA (US). She has made significant contributions to the field of pharmaceutical chemistry, particularly in the development of compounds that target alpha 1A adrenoceptors. With a total of 4 patents to her name, her work has the potential to improve treatments for conditions such as benign prostatic hyperplasia.
Latest Patents
Nerenberg's latest patents include innovative compounds that serve as alpha 1A adrenoceptor antagonists. One of her notable inventions is a series of oxazolidinone compounds, which are designed to selectively relax smooth muscle tissue enriched in the alpha 1A receptor subtype. This selectivity allows for the treatment of benign prostatic hyperplasia without inducing hypotension, providing acute relief to males by facilitating less hindered urine flow. Additionally, these compounds can be combined with human 5-alpha reductase inhibitors for both acute and chronic relief from the effects of the condition.
Another significant patent involves pyrimidinedione derivatives, which also function as alpha 1A adrenoceptor antagonists. Similar to her oxazolidinone compounds, these pyrimidinedione compounds are designed to relax smooth muscle tissue without causing hypotension, thus offering therapeutic benefits for those suffering from benign prostatic hyperplasia.
Career Highlights
Nerenberg is currently associated with Merck & Co., Inc., where she continues to advance her research in pharmaceutical innovations. Her work has been instrumental in developing new therapeutic options that enhance patient care and treatment outcomes.
Collaborations
Throughout her career, Nerenberg has collaborated with esteemed colleagues, including Mark G Bock and Harold G Selnick. These collaborations have contributed to the successful development of her patented compounds and have fostered a collaborative environment for innovation.
Conclusion
Jennie B Nerenberg's contributions to pharmaceutical chemistry exemplify the impact of innovative research on healthcare. Her patents not only advance scientific knowledge but also provide practical solutions for improving patient treatment options.