This inventor holds 1 USPTO granted patent. Top assignee: Lynx Therapeutics, Inc.. Active years: 1999.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1999
Title: The Innovative Contributions of Jeffrey S. Nelson
Introduction
Jeffrey S. Nelson is a notable inventor based in Fremont, CA (US). He has made significant contributions to the field of oligonucleotide synthesis, particularly through his innovative patent. His work has implications for various applications in biotechnology and pharmaceuticals.
Latest Patents
One of Jeffrey S. Nelson's key patents is titled "Synthons for synthesis of oligonucleotide N3-P5 phosphoramidates." This invention provides a method for synthesizing oligonucleotide N3'.fwdarw.P5' phosphoramidates using an amine-exchange reaction of phosphoramidites. The process involves exchanging a deprotected 3'-amino group of a solid-phase supported oligonucleotide chain for the amino portion of a 5'-phosphoramidite of an incoming monomer, which has a protected 3'-amino group. The resulting internucleotide phosphoramidite linkage is then oxidized to form a stable protected phosphoramidate linkage. This method greatly improves product yields and reduces reagent usage compared to currently available methods for synthesizing this class of compounds. Jeffrey holds 1 patent.
Career Highlights
Jeffrey S. Nelson has been associated with Lynx Therapeutics, Inc., where he has contributed to advancements in oligonucleotide synthesis. His work has been instrumental in enhancing the efficiency and effectiveness of oligonucleotide production, which is crucial for various research and therapeutic applications.
Collaborations
Throughout his career, Jeffrey has collaborated with notable colleagues, including Bernard L. Hirschbein and Karen L. Fearon. These collaborations have further enriched his work and contributed to the success of his innovative projects.
Conclusion
Jeffrey S. Nelson's contributions to the field of oligonucleotide synthesis through his innovative patent demonstrate his commitment to advancing biotechnology. His work not only improves product yields but also reduces reagent usage, showcasing the importance of innovation in scientific research.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile