Gainesville, FL, United States of America

Jeffrey K Harrison

USPTO Granted Patents = 4 

Average Co-Inventor Count = 5.2

ph-index = 2

Forward Citations = 27(Granted Patents)


Location History:

  • Gainesville, FL (US) (1996 - 1997)
  • Keswick, VA (US) (1997)

Company Filing History:


Years Active: 1996-1997

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4 patents (USPTO):Explore Patents

Title: The Innovations of Jeffrey K. Harrison

Introduction

Jeffrey K. Harrison is a notable inventor based in Gainesville, FL (US). He has made significant contributions to the field of biotechnology, particularly in the study of growth hormone releasing hormone (GHRH) and its receptor. With a total of 4 patents to his name, Harrison's work has advanced our understanding of hormonal interactions and their implications in various biological processes.

Latest Patents

Harrison's latest patents focus on the cloning of a gene encoding for the growth hormone releasing hormone. His innovative approach includes the characterization of GHRH receptor binding using a unique binding assay with iodinated GHRH probes. He has developed photoaffinity GHRH probes that facilitate photolabeling and characterization of the receptor. Additionally, he has constructed high affinity biotinylated GHRH analogs. His methods for solubilizing GHRH-R/GHRH complexes and extracting specifically bound GHRH using mild detergent solutions, followed by affinity chromatography, lead to a substantially purified GHRH-R isolate. The electrophoretic treatment of this isolate allows for sequencing of the receptor, further enhancing the understanding of its function. Cloning of a gene encoding for polypeptides with GHRH-R activity is achieved using a bacterial host, with expression in a mammalian cell line.

Career Highlights

Throughout his career, Harrison has worked with prestigious institutions, including the University of Virginia and American Cyanamid Company. His research has not only contributed to academic knowledge but has also had practical applications in the biotechnology industry.

Collaborations

Harrison has collaborated with notable colleagues such as John R. Zysk and Michael Oliver Thorner. These partnerships have enriched his research and expanded the impact of his innovations.

Conclusion

Jeffrey K. Harrison's contributions to the field of biotechnology, particularly in the area of growth hormone releasing hormone research, highlight his role as a significant inventor. His innovative patents and collaborations continue to influence the scientific community and pave the way for future advancements.

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