This inventor holds 2 USPTO granted patents. Top assignees: Chiron Diagnostics Corporation, Ciba Corning Diagnostics Corp.. Active years: 1995-1999.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
1 out of 67 
1 out of 94 Years Active: 1995-1999
Title: Innovations by Jeffrey J Donahue
Introduction
Jeffrey J Donahue is an accomplished inventor based in Wayland, MA (US). He holds 2 patents that contribute significantly to the field of DNA amplification. His work focuses on developing new methods for detecting target nucleic acid sequences in test samples.
Latest Patents
One of his latest patents involves the amplification of midivariant DNA templates. This innovative method provides new techniques for amplifying midivariant DNA that contains inserted target-specific nucleic acid sequences. The goal is to enable the detection of target nucleic acid sequences in various test samples. One method utilizes midivariant DNA as a template for RNA synthesis, catalyzed by QB replicase. The patent describes two midivariant DNA/probe conjugates, which include a nonreplicable portion of midivariant DNA and a target-specific nucleic acid sequence. The amplification method consists of hybridization and ligation of these conjugates, followed by replication of the DNA template. This method has successfully enabled the detection of less than 200 template molecules. In a modified approach, one of the conjugates includes an RNA polymerase promoter sequence, allowing for the transcription of the midivariant DNA template into RNA. This sequential ligation-transcription-replication method can detect a single template molecule, indicating the presence of target nucleic acid sequences in the test sample.
Career Highlights
Throughout his career, Jeffrey has worked with notable companies such as Ciba Corning Diagnostics Corporation and Chiron Diagnostics Corporation. His experience in these organizations has contributed to his expertise in the field of diagnostics and DNA technology.
Collaborations
Some of his notable coworkers include John T Unger and Richard A Martinelli. Their collaboration has likely fostered innovative ideas and advancements in their respective fields.
Conclusion
Jeffrey J Donahue's contributions to DNA amplification and detection methods highlight his role as a significant inventor in the biotechnology sector. His innovative approaches continue to influence the field and pave the way for future advancements.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile