Jeffrey I Stein

Title: The Innovative Contributions of Jeffrey I Stein

Introduction

Jeffrey I Stein is a notable inventor based in Chapel Hill, NC (US). He has made significant contributions to the field of agricultural biotechnology, particularly in the production of hybrid seeds. With a total of 5 patents to his name, Stein's work has had a considerable impact on the industry.

Latest Patents

One of Stein's latest patents focuses on methods for the production of hybrid seed. This invention provides a dual method for producing male-sterile plants. The process involves crossing two genetically transformed plants, referred to as parents 1 and 2, to obtain male-sterile offspring. Parent 1 is transformed with an expression cassette that includes a nucleotide sequence encoding an anther-specific promoter, which is operably linked to a nucleotide sequence encoding a transactivator. Parent 2 is transformed with an expression cassette that comprises a target nucleotide sequence, capable of being activated by the transactivator, operably linked to a nucleotide sequence encoding RNA or a polypeptide that disrupts the formation of viable pollen. The result of crossing parent 1 with parent 2 is male-sterile offspring, which are useful for producing hybrid seed. Another significant patent involves genomic DNA encoding a Pseudomonas global transcriptional activation. This patent provides gene activating sequences that enhance the expression of other bacterial genes, which may be latent or expressed at low levels. The transformed biocontrol agents are effective in inhibiting the growth of fungal pathogens.

Career Highlights

Throughout his career, Jeffrey I Stein has worked with prominent companies in the biotechnology sector. Notably, he has been associated with Novartis Finance Corporation and Ciba-Geigy Corporation. His experience in these organizations has contributed to his expertise in the field.

Collaborations

Stein has collaborated with several professionals in his field, including Lyle Dean Crossland and Annmarie B Tuttle. These collaborations have likely enriched his research and development efforts.

Conclusion

Jeffrey I Stein's innovative work in agricultural biotechnology, particularly in hybrid seed production, showcases his significant contributions to the field. His patents reflect a commitment to advancing agricultural practices through scientific innovation.