Jeffrey I Krieger

Title: Jeffrey I Krieger: Innovator in Immunosuppressive Compounds

Introduction

Jeffrey I Krieger is a notable inventor based in Newton, MA (US). He has made significant contributions to the field of immunology through his innovative research and development of novel compounds. His work focuses on creating effective immunosuppressive agents that can aid in organ and bone marrow transplantation.

Latest Patents

Krieger holds a patent for "Aromatic compounds for inhibiting immune response." This patent describes novel compounds wherein R.sup.1 to R.sup.13 are independently selected from C.sub.2 -C.sub.4 linear and branched alkyls, H, NH.sub.2, CH.sub.3, OR.sup.14, fluorine, chlorine, iodine, NO.sub.2, CF.sub.3, NHCOCH.sub.3, NHCOOtBu, NHR.sup.15, NR.sup.16 R.sup.17, and phenyl. These compounds are designed for use as immunosuppressive agents to prevent or significantly reduce graft rejection in organ and bone marrow transplantation. Additionally, they can be utilized as immunosuppressant drugs for T-lymphocyte mediated autoimmune diseases, such as diabetes, and may also alleviate conditions like psoriasis and contact dermatitis. Furthermore, these compounds have potential applications in antiproliferation and gene therapy.

Career Highlights

Krieger is associated with Procept Corporation, where he continues to advance his research in immunology. His work has garnered attention for its potential to improve patient outcomes in transplantation and autoimmune disease management.

Collaborations

Some of his notable coworkers include Timothy D Ocain and Huai Gao, who contribute to the innovative environment at Procept Corporation.

Conclusion

Jeffrey I Krieger's contributions to the field of immunology through his patented compounds highlight his role as a significant inventor. His work not only addresses critical medical challenges but also paves the way for future advancements in immunosuppressive therapies.