Location History:
- Boston, MA (US) (1997)
- Mill Valley, CA (US) (2021)
- Newton, MA (US) (2007 - 2024)
Company Filing History:
12 out of 2,882 
8 out of 1,206 
2 out of 1,309 
Years Active: 1997-2024
Title: Innovations and Contributions of Jeffrey E Settleman
Introduction
Jeffrey E Settleman is a prominent inventor based in Newton, MA (US), known for his significant contributions to cancer research and treatment. With a total of 12 patents, his work focuses on developing methods and reagents that enhance the effectiveness of cancer therapies.
Latest Patents
Among his latest patents is a method to determine the responsiveness of cancer to epidermal growth factor receptor targeting treatments. This patent discloses methods and reagents for assessing the responsiveness of cancer to epidermal growth factor receptor (EGFR) targeting treatments. The detection of specific mutations allows for the administration of gefitinib, erlotinib, and other tyrosine kinase inhibitors to patients most likely to benefit from these drugs. Another notable patent involves biomarkers of response to NAE inhibitors, which identifies markers whose mutational status is associated with sensitivity to treatment with NAE inhibitors. This innovation provides compositions and methods to assess markers of marker genes to predict responses to NAE inhibition treatment.
Career Highlights
Throughout his career, Jeffrey has worked with esteemed organizations such as The General Hospital Corporation and Dana-Farber Cancer Institute Inc. His research has significantly impacted the field of oncology, particularly in personalizing cancer treatment based on genetic markers.
Collaborations
Jeffrey has collaborated with notable colleagues, including Daphne Winifred Bell and Daniel Arie Haber, contributing to advancements in cancer research and treatment methodologies.
Conclusion
Jeffrey E Settleman’s innovative work and numerous patents reflect his dedication to improving cancer treatment through scientific research. His contributions continue to influence the field and offer hope for more effective therapies for cancer patients.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.