Company Filing History:
Years Active: 1988
Title: The Innovations of Jeffrey E. Flatgaard
Introduction
Jeffrey E. Flatgaard is a notable inventor based in Berkeley, California. He has made significant contributions to the field of biotechnology, particularly in the development of enzymes. His work has implications for various industries, including biofuels and pharmaceuticals.
Latest Patents
One of his key patents is related to Glucoamylase CDNA. This invention involves a gene with a DNA sequence that is complementary to the glucoamylase polypeptide mRNA derived from the fungal species Aspergillus awamori. The mRNA is approximately 2.2 kilobases of poly A RNA obtained from fungal cells that have been grown under conditions that induce glucoamylase production. The reverse transcription of this mRNA results in a glucoamylase probe that is used to identify genomic digest fragments containing glucoamylase gene regions. These fragments are sequenced to locate introns and exons, which are then spliced together to form a gene with an altered or deleted intron sequence. This gene codes for a fungal glucoamylase protein that can express a non-native protein with glucoamylase enzyme activity when combined with a cleaved DNA expression vector. The transformed host, preferably bacteria or yeast, can be utilized to produce ethanol.
Career Highlights
Jeffrey E. Flatgaard has worked at Cetus Corporation, where he has been involved in groundbreaking research and development. His expertise in molecular biology and genetics has positioned him as a valuable asset in the field.
Collaborations
Throughout his career, Flatgaard has collaborated with notable colleagues, including Jack H. Nunberg and Michael A. Innis. These partnerships have fostered innovation and contributed to advancements in biotechnology.
Conclusion
Jeffrey E. Flatgaard's contributions to the field of biotechnology, particularly through his patent on Glucoamylase CDNA, highlight his role as an influential inventor. His work continues to impact various industries, showcasing the importance of innovation in science and technology.