Location History:
- New Haven, CT (US) (2010)
- Lansing, MI (US) (2013)
Company Filing History:
Years Active: 2010-2013
Title: Innovations of Jeffrey E Barrick
Introduction
Jeffrey E Barrick is a notable inventor based in Lansing, MI (US). He has made significant contributions to the field of genetic engineering, particularly through his work on riboswitches. With a total of two patents to his name, Barrick's innovations have the potential to revolutionize gene therapy and metabolic engineering.
Latest Patents
Barrick's latest patents focus on riboswitches, which are natural mRNAs that act as metabolite-sensitive genetic switches. These riboswitches bind small organic molecules, leading to conformational changes in the mRNA that affect gene expression. By employing various nucleic acid engineering strategies, modified versions of these riboswitches can be created as designer genetic switches controlled by specific effector compounds, known as trigger molecules. The natural riboswitches serve as targets for antibiotics and small molecule therapies. Furthermore, the architecture of riboswitches allows for the construction of new non-immunogenic genetic control elements, enabling the modulation of gene expression with user-defined compounds. This innovation has applications in living biosensors, metabolic engineering, and advanced gene therapy treatments.
Career Highlights
Jeffrey E Barrick is affiliated with Yale University, where he continues to advance research in genetic regulation. His work has garnered attention for its potential applications in therapeutic settings, particularly in the development of new treatment regimens that can regulate protein synthesis.
Collaborations
Barrick has collaborated with notable researchers such as Ronald R Breaker and Ali Nahvi. These collaborations have further enriched his research and contributed to the advancements in the field of genetic engineering.
Conclusion
Jeffrey E Barrick's innovative work on riboswitches exemplifies the intersection of genetic engineering and therapeutic applications. His contributions are paving the way for new approaches in gene therapy and metabolic engineering, showcasing the importance of his research in modern science.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.