Jeffrey D Ahlers

Title: The Innovative Contributions of Jeffrey D Ahlers

Introduction

Jeffrey D Ahlers is a notable inventor based in Kensington, MD (US). He has made significant contributions to the field of immunology, particularly in the development of peptide constructs aimed at eliciting immune responses against HIV. With a total of 4 patents, Ahlers has demonstrated a commitment to advancing medical science through innovative research.

Latest Patents

Ahlers' latest patents include groundbreaking work on peptides that elicit a high neutralizing antibody titer, cytotoxic T lymphocyte response, and T helper cell response across a broad range of MHC type recipients. One of his notable inventions involves peptide constructs comprised of multideterminant T helper peptides from the envelope glycoprotein of HIV. These constructs have been shown to induce proliferative responses in various haplotypes of mice and IL-2 responses in a significant percentage of HIV positive patients. His research indicates that after a single immunization, the level of neutralizing antibody achieved was comparable to levels adequate for protection from homologous viral challenges in chimpanzees.

Career Highlights

Throughout his career, Ahlers has worked with prestigious organizations, including the National Institutes of Health, a component of the US Department of Health & Human Services. His work has been pivotal in advancing our understanding of immune responses to HIV, contributing to the development of potential therapeutic strategies.

Collaborations

Ahlers has collaborated with esteemed colleagues such as Jay A Berzofsky and Peter L Nara, further enhancing the impact of his research in the field of immunology.

Conclusion

Jeffrey D Ahlers stands out as an influential inventor whose work in peptide constructs has the potential to significantly impact the fight against HIV. His innovative contributions continue to pave the way for advancements in immunological research and therapies.