Chapel Hill, NC, United States of America

Jeffery M Vance

USPTO Granted Patents = 12 


Average Co-Inventor Count = 3.4

ph-index = 3

Forward Citations = 21(Granted Patents)


Location History:

  • Durham, NC (US) (1998)
  • Chapel Hill, NC (US) (2010 - 2016)
  • Coral Gables, FL (US) (2010 - 2022)

Company Filing History:


Years Active: 1998-2022

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12 patents (USPTO):Explore Patents

Title: Inventor Jeffery M. Vance: Pioneering Advances in Genetic Research

Introduction

Jeffery M. Vance, located in Chapel Hill, NC, is an esteemed inventor with a focus on the field of genetics and innovative methods for diagnosing diseases. With a remarkable portfolio of 12 patents, Vance has made significant contributions to the understanding and early detection of neurological and kidney disorders.

Latest Patents

Among his latest patents, Vance has developed methods for detecting Charcot-Marie-Tooth disease Type 2A. This invention describes techniques for screening subjects for risk and diagnosing the disease by detecting mutations in the mitofusin gene from biological samples. Furthermore, he has also created methods to identify a genetic polymorphism associated with the disease through the amplification of mitofusin gene sequences.

Another noteworthy patent focuses on the role of the TRPC6 gene in glomerulonephritis, particularly in Focal Segmental Glomerulosclerosis (FSGS). This kidney disorder affects patients, many of whom are on dialysis. Vance's research uncovered a missense mutation in the TRPC6 gene that enhances calcium signaling in response to specific stimuli, suggesting a novel mechanism for disease pathogenesis.

Career Highlights

Jeffery M. Vance is associated with Duke University, where he leverages his expertise to further research and innovation in genetics. His work has not only challenged existing paradigms in understanding genetic disorders but also provided valuable insights that could lead to better diagnostic techniques.

Collaborations

Throughout his career, Vance has partnered with notable colleagues such as Margaret A. Pericak-Vance and Michelle Winn. Their collaboration has undoubtedly enriched the research environment, fostering innovation within the realm of genetic studies and improving outcomes for individuals affected by hereditary diseases.

Conclusion

Jeffery M. Vance exemplifies the spirit of innovation within the genetic research field. With his 12 patents, he continues to push the boundaries of science, leading to enhanced disease detection methods that could significantly impact patient care. As he collaborates with other experts, Vance's contributions serve as an inspiration for future inventors and researchers aiming to make a difference in medical science.

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