Location History:
- Redwood City, CA (US) (2004)
- Burlingame, CA (US) (1997 - 2006)
Company Filing History:
Years Active: 1997-2006
Title: Jeff Pudlo: Innovator in Oligomer Technology
Introduction
Jeff Pudlo is a notable inventor based in Burlingame, California, with a significant contribution to the field of oligomer technology. He holds a total of 10 patents, showcasing his innovative approach to enhancing the formation of duplexes and triplexes in nucleic acids.
Latest Patents
One of his latest patents focuses on "Enhanced triple-helix and double-helix formation with oligomers containing modified pyrimidines." This invention discloses novel oligomers that exhibit an enhanced ability to form duplexes or triplexes compared to those containing only conventional bases. The oligomers incorporate bases such as 5-(1-propynyl)uracil and 5-(1-propynyl)cytosine. These oligomers can form triplexes with various target sequences, including virus or oncogene sequences, by coupling into the major groove of a target DNA duplex at physiological pH. Additionally, they can bind to single-stranded DNA or RNA encoded by target genes. The compositions can be incorporated into pharmaceutically acceptable carriers and are designed to treat diseases caused by viruses, as well as for diagnostic purposes.
Career Highlights
Throughout his career, Jeff Pudlo has worked with prominent companies in the biotechnology sector, including Isis Pharmaceuticals, Inc. and Gilead Sciences, Inc. His work has significantly impacted the development of therapeutic agents and diagnostic tools.
Collaborations
Some of his notable coworkers include Robert J. Jones and Mark D. Matteucci, who have contributed to his innovative projects and research endeavors.
Conclusion
Jeff Pudlo's contributions to the field of oligomer technology and his innovative patents highlight his role as a leading inventor in the biotechnology industry. His work continues to pave the way for advancements in pharmaceutical applications and diagnostics.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.