Company Filing History:
2 out of 6 
1 out of 2 
1 out of 4 Years Active: 2003-2014
Title: The Innovative Contributions of Inventor Jean-Pierre Marie
Introduction
Jean-Pierre Marie, a remarkable inventor based in Sèvres, France, has made significant contributions to the field of chemistry and pharmaceuticals. With an impressive portfolio of five patents, his work focuses primarily on the development of alkaloids used in chemotherapy, particularly through innovative processes that enhance their purity and efficacy.
Latest Patents
Among his latest patents is the groundbreaking work on cephalotaxane derivatives. This invention outlines a new general process for the asymmetric hemisynthesis of harringtonines and their analogs. These compounds are notable for their usage in chemotherapy. The process detailed in the patent involves the direct esterification of a natural cephalotaxine with an acylating compound that includes preformed side chain precursors. The invention not only addresses the synthesis of natural, synthetic, or semi-synthetic harringtonines but also ensures that the total content of impurities, including enantiomeric forms, remains below 1%. Moreover, it stipulates that the major impurity content stays below 0.9%, and the chromatographic assay demonstrates a harringtonines content exceeding 97.5%.
Career Highlights
Jean-Pierre Marie has contributed his expertise to several notable companies throughout his career, including Stragen Pharma SA and Oncopharm Corporation. His work within these organizations has further advanced the research and development of chemotherapeutic agents, showcasing his dedication to improving patient outcomes through innovative pharmaceutical solutions.
Collaborations
Throughout his professional journey, Jean-Pierre has collaborated with distinguished colleagues such as Jean-Pierre Robin and Nina Radosevic. These collaborations have enhanced his research efforts and enabled him to share insights and knowledge, culminating in the successful development of various innovative applications in the pharmaceutical field.
Conclusion
In summary, Jean-Pierre Marie stands out as a prominent figure in the realm of innovation, particularly in the synthesis and purification of alkaloids for chemotherapy. His commitment to advancing medical science through his inventive processes highlights the importance of patents in protecting and promoting groundbreaking inventions that can have a profound impact on healthcare and patient treatment options.