Company Filing History:
Years Active: 1976-1977
Title: The Innovations of Jean Pierre Lefevre
Introduction
Jean Pierre Lefevre is a notable inventor based in Paris, France. He has made significant contributions to the field of medicinal chemistry, particularly in the development of compounds that address circulatory disorders. With a total of 2 patents, Lefevre's work has the potential to impact therapeutic practices.
Latest Patents
Lefevre's latest patents include the invention of Vincaminic acid amides. This invention provides compounds of a specific formula wherein A and B are hydrogen, and R can be hydrogen or cycloalkyl. These compounds are useful in treating pathological disturbances involving an anoxia factor. Another significant patent is the process for the preparation of cis-vincamine. This process involves oxidizing trans-vincamine with tertiary butyl hypochlorite to obtain dehydrovincamine chloride, followed by reducing the chloride with a metal in an aqueous acidic medium. The resulting product is neutralized, and cis-vincamine is separated from the mixture of cis- and trans-vincamines. Cis-vincamine is particularly useful for treating circulatory disorders.
Career Highlights
Lefevre is currently associated with Synthelabo, a company known for its focus on pharmaceutical innovations. His work at Synthelabo has allowed him to explore and develop new therapeutic compounds that can significantly improve patient outcomes.
Collaborations
Throughout his career, Lefevre has collaborated with notable colleagues such as Henry Najer and Don Pierre Giudicelli. These collaborations have fostered an environment of innovation and creativity, leading to advancements in their respective fields.
Conclusion
Jean Pierre Lefevre's contributions to medicinal chemistry through his patents and collaborations highlight his role as an influential inventor. His work continues to pave the way for new treatments in the medical field.