Location History:
- Houston, TX (US) (2004 - 2008)
- Timonium, MD (US) (2010 - 2012)
Company Filing History:
Years Active: 2004-2012
Title: Innovations of Jean-Pierre Issa
Introduction
Jean-Pierre Issa is a prominent inventor based in Timonium, MD (US). He has made significant contributions to the field of molecular biology, particularly in the area of methylated nucleic acids. With a total of 4 patents to his name, Issa's work has the potential to impact various medical and research applications.
Latest Patents
One of Issa's latest patents is focused on Methylated CpG Island Amplification (MCA). This invention provides a method for identifying a methylated CpG containing nucleic acid by utilizing a methylation-sensitive restriction endonuclease that cleaves unmethylated CpG sites. The process involves contacting the nucleic acid sample with an isoschizomer of the restriction endonuclease, which can cleave both methylated and unmethylated CpG sites. Additionally, the method includes the amplification of the CpG-containing nucleic acid using CpG-specific oligonucleotide primers. This innovation also offers a method for detecting age-associated disorders through the identification of methylated CpG containing nucleic acids. Furthermore, it provides a means for evaluating cellular responses to various agents, along with a kit designed for the detection of CpG containing nucleic acids.
Career Highlights
Jean-Pierre Issa is affiliated with The Johns Hopkins University, where he continues to advance his research and innovations. His work has garnered attention in the scientific community, contributing to the understanding of epigenetics and its implications in health and disease.
Collaborations
Issa has collaborated with notable researchers in his field, including Stephen B. Baylin and Minoru Toyota. These collaborations have further enriched his research and expanded the impact of his inventions.
Conclusion
Jean-Pierre Issa's contributions to the field of molecular biology through his innovative patents highlight the importance of research in understanding complex biological processes. His work continues to pave the way for advancements in medical diagnostics and therapeutic strategies.