Company Filing History:
Years Active: 2005-2016
Title: Innovations of Jean Philippe Pellois in Oligonucleotide Synthesis
Introduction
Jean Philippe Pellois is a notable inventor based in New York, NY (US). He has made significant contributions to the field of oligonucleotide synthesis and purification. With a total of 7 patents to his name, Pellois has developed innovative methods that enhance the efficiency and effectiveness of synthetic processes.
Latest Patents
One of his latest patents focuses on "Linkers and co-coupling agents for optimization of oligonucleotide synthesis and purification on solid supports." This method describes a modulation of synthesis capacity and cleavage properties of synthetic oligomers from solid support. The technique utilizes linker molecules attached to a solid surface and co-coupling agents that exhibit similar reactivities to the coupling compounds with the surface functional groups. The preferred linker molecules increase the density of polymers and enhance resistance to cleavage from the support surface. This method is particularly beneficial for the synthesis of oligonucleotides, oligonucleotide microarrays, peptides, and peptide microarrays. The stable linkers are also coupled to anchor molecules for the synthesis of DNA oligonucleotides using on-support purification, which eliminates the need for time-consuming chromatography and the presence of metal cations. The oligonucleotides produced can be directly utilized for mass analysis, DNA amplification and ligation, hybridization, and various other applications.
Career Highlights
Throughout his career, Jean Philippe Pellois has worked with prestigious institutions, including the University of Michigan. His work has significantly impacted the field of biotechnology and molecular biology.
Collaborations
Pellois has collaborated with notable individuals in his field, including Xiaolian Gao and Hua Zhang. Their joint efforts have contributed to advancements in oligonucleotide research and applications.
Conclusion
Jean Philippe Pellois is a distinguished inventor whose work in oligonucleotide synthesis has paved the way for innovative methodologies in biotechnology. His contributions continue to influence the field and enhance research capabilities.