Jean M Arrang

Title: Jean M Arrang: Innovator in Histamine Agonist Research

Introduction

Jean M Arrang is a notable inventor based in Gif sur Yvette, France. He has made significant contributions to the field of pharmacology, particularly in the development of drugs that act on histamine receptors. His work has implications for various therapeutic applications, including sleep induction and anti-inflammatory treatments.

Latest Patents

Jean M Arrang holds a patent for a method of inducing a histamine agonist action on H₂ receptors. The invention claims drugs that are active as agonists of the histamine H₃ receptor, including O-[2-(4(5-imidazolyl)-ethyl] isothiourea, 4-(4(5)-imidazolyl) butyramidine, and S-[2-(4(5)-imidazolyl)-ethyl] isourea, along with their N-methyl derivatives. These compounds are useful for preparing drugs intended for use as hypnotics, sleep inducers, tranquilizers, sedatives, anxiolytics, anti-asthmatics, and anti-inflammatory agents, particularly for the bronchi, skin, or eyes, as well as for treating gastric ulcers.

Career Highlights

Throughout his career, Jean M Arrang has worked with prominent organizations such as Société Civile Bioprojet and the Institut National de la Santé et de la Recherche Médicale. His research has focused on the pharmacological effects of histamine and its receptors, contributing to advancements in medical treatments.

Collaborations

Jean M Arrang has collaborated with notable colleagues, including Jean Charles Schwartz and Monique Garbarg. These partnerships have facilitated the exchange of ideas and expertise, enhancing the impact of their research in the field.

Conclusion

Jean M Arrang's innovative work in histamine receptor research has led to valuable patents and collaborations that advance medical science. His contributions continue to influence the development of therapeutic agents for various health conditions.