Jean-Luc Pellequer

Title: Innovations of Jean-Luc Pellequer

Introduction

Jean-Luc Pellequer is a notable inventor based in France, recognized for his contributions to the field of biochemistry. He holds two patents that focus on the stabilization of proteins through innovative methods. His work has significant implications for pharmaceutical applications and protein engineering.

Latest Patents

Jean-Luc Pellequer's latest patents revolve around the concept of stabilized proteins with engineered disulfide bonds. The inventions detail methods for introducing cysteine residues into polypeptides, which allow for the stabilization of these proteins by forming disulfide bonds between different domains. This technology encompasses polypeptides that include plasma proteins, such as hepatocyte growth factor activator and plasma hyaluronin binding protein, as well as critical blood coagulation factors like Factor VIII, Factor V, Factor XII, and prothrombin. The patents also cover nucleic acids encoding these polypeptides, pharmaceutical compositions, and methods for producing the polypeptides using vectors, viral particles, and host cells.

Career Highlights

Jean-Luc Pellequer is affiliated with The Scripps Research Institute, a prestigious organization known for its cutting-edge research in the life sciences. His work at this institute has allowed him to explore innovative approaches to protein stabilization and engineering.

Collaborations

Throughout his career, Jean-Luc Pellequer has collaborated with esteemed colleagues, including John H Griffin and Andrew Gale. These partnerships have contributed to the advancement of his research and the successful development of his patented technologies.

Conclusion

Jean-Luc Pellequer's innovative work in protein stabilization through engineered disulfide bonds showcases his significant contributions to biochemistry and pharmaceutical sciences. His patents reflect a commitment to advancing the field and improving therapeutic applications.