Company Filing History:
Years Active: 1995
Title: Janis L Klotz: Innovator in Tissue Fixation Technology
Introduction
Janis L Klotz is a notable inventor based in Tucson, AZ, recognized for his contributions to the field of tissue fixation. His innovative work has led to the development of a bisulfite-based tissue fixative that enhances the quality of tissue samples used in immunohistochemical analysis.
Latest Patents
Klotz holds a patent for a bisulfite-based tissue fixative, which significantly improves morphology, antigen retention, and antigenicity. This fixative is particularly suitable for sections of frozen tissue, cytology preparations, and other specimens. The invention comprises an acidic buffer and a bisulfite salt in effective amounts for optimal tissue fixation. In a preferred embodiment, the fixative contains a bisulfite salt concentration ranging from about 0.01 to about 0.25M, ideally between 0.02 to 0.25M, within an acidic buffer having a pH of about 2 to about 6.
Career Highlights
Janis L Klotz is associated with Ventana Medical Systems, Inc., where he has made significant strides in the development of tissue fixation technologies. His work has been instrumental in advancing the methodologies used in histopathology and related fields.
Collaborations
Klotz has collaborated with notable colleagues, including Anthony L Hartman and Christine R Jones, who have contributed to his research and development efforts.
Conclusion
Janis L Klotz's innovative contributions to tissue fixation technology have made a lasting impact in the field of immunohistochemistry. His work continues to enhance the quality and reliability of tissue analysis, showcasing the importance of innovation in medical research.