Jang Gi Choi

Title: Jang Gi Choi: Inventor in Tumor Immunotherapy

Introduction

Jang Gi Choi is an inventor based in Daegu, South Korea. He is associated with the Korea Institute of Oriental Medicine and is named on 1 patent concerning a composition intended to inhibit tumor proliferation.

Latest Patents

Choi’s patent, “Composition for Inhibiting Proliferation of Tumor Comprising Extract as Effective Component,” describes an extract-based composition designed to support anti-tumor immune activity. According to the provided patent description, the extract binds to PD-L1 on cancer cells, blocking its interaction with PD-1 on T cells. This mechanism is reported to activate T cells and inhibit tumor proliferation.

The description also reports anti-tumor immune activity in a humanized PD-1 animal model using MC38 colorectal cancer cells expressing human PD-L1. It further notes a synergistic effect when the composition is administered alongside anti-cancer agents.

Career Highlights

Choi’s listed work connects research at the Korea Institute of Oriental Medicine with an approach to cancer immunotherapy. The patent focuses on disrupting the PD-L1 and PD-1 interaction and investigating the extract’s potential in combination with existing anti-cancer treatments.

Collaborations

Hwan Suck Chung and Ji Hye Kim are identified as Choi’s coworkers. The provided information does not specify their roles in the patent or the research.

Conclusion

Jang Gi Choi’s listed patent presents an extract-based strategy for activating T cells and inhibiting tumor growth, with reported activity in a humanized animal model and potential for combination with anti-cancer agents.