Location History:
- Bergisch Gladbach, DE (2001)
- Bergheim, DE (2002)
Company Filing History:
1 out of 58 
1 out of 832,891 Years Active: 2001-2002
Title: Jürgen Schmitz: Innovator in Magnetic Cell Separation
Introduction
Jürgen Schmitz is a notable inventor based in Bergheim, Germany. He has made significant contributions to the field of cell separation technology, particularly through his innovative methods that enhance the efficiency of isolating specific cells from heterogeneous mixtures. With a total of 2 patents, Schmitz's work has implications in medical diagnostics and research.
Latest Patents
One of Schmitz's latest patents is titled "Methods of modification of selected cells in a magnetic cell separation column." This patent describes a method for modifying cells that are retained in a high gradient magnetic cell separation column (HGMS). In this process, selected cells within a mixture are labeled with a magnetic particle that is specific to those cells. The labeled cells are then applied to the magnetic column, where they are retained and subsequently modified before being removed to either the original suspension or a purified, homogeneous suspension.
Another significant patent is "Efficient enrichment and detection of disseminated tumor cells." This invention focuses on the separation of tumor cells, particularly carcinoma cells, from peripheral blood using magnetic sorting. The tumor cells are magnetically labeled with antibodies that target tissue-specific antigens, preferably cytoplasmic proteins. The process involves permeabilizing and fixing the cells before they are separated on a magnetic matrix. The number of tumor cells in the enriched fraction is then used to estimate the total number of tumor cells present in a patient's hematopoietic sample.
Career Highlights
Throughout his career, Jürgen Schmitz has worked with various companies, including Miltenyi Biotec GmbH. His expertise in magnetic cell separation has positioned him as a key figure in advancing technologies that improve cell isolation and analysis.
Collaborations
Schmitz has collaborated with notable individuals in the field, including Stefan Miltenyi and Fawn Qian. These partnerships have contributed to the development of innovative solutions in cell separation technology.
Conclusion
Jürgen Schmitz's contributions to the field of magnetic cell separation are significant and impactful. His patents reflect a commitment to advancing medical diagnostics and research methodologies. Through his innovative approaches, Schmitz continues to influence the landscape of cell separation technology.