This inventor holds 1 USPTO granted patent. Top assignee: Cancer Therapy and Research Center. Active years: 1996.
Company Filing History:
Years Active: 1996
Title: Jan M Woynarowski: Innovator in Antitumor Agents
Introduction
Jan M Woynarowski is a notable inventor based in San Antonio, TX (US). He has made significant contributions to the field of cancer research, particularly in the development of novel antitumor agents. His work focuses on innovative compounds that have the potential to improve cancer treatment outcomes.
Latest Patents
Woynarowski holds a patent for "Diamine platinum naphthalimide complexes as antitumor agents." This invention provides novel bis-naphthalimides characterized by having a linker containing a heteroatom. The preparation and pharmaceutical compositions of these bis-naphthalimides are detailed, along with various methods of using them. Particularly preferred bis-naphthalimides have a linker of about 8-16 atoms where the heteroatom is oxygen, sulfur, sulfur oxide, or sulfur dioxide. These compounds exhibit exceptional DNA binding properties and demonstrate cytotoxicity in both in vitro and in vivo tumor models, especially against melanoma. Additionally, the patent includes novel mono-naphthalimides linked to a DNA alkylating agent, which show conformational effects on double-stranded DNA and form covalent adducts after extended incubation periods.
Career Highlights
Woynarowski is affiliated with the Cancer Therapy and Research Center, where he continues to advance his research in cancer therapeutics. His innovative work has positioned him as a key figure in the development of new treatment modalities for cancer patients.
Collaborations
Throughout his career, Woynarowski has collaborated with esteemed colleagues, including Alexander L Weis and Shih-Fong Chen. These collaborations have further enriched his research and contributed to the advancement of cancer treatment strategies.
Conclusion
Jan M Woynarowski's contributions to the field of antitumor agents highlight his commitment to improving cancer therapies. His innovative patents and collaborations underscore the importance of research in the fight against cancer.