Company Filing History:
2 out of 878 
1 out of 5,448 
Years Active: 2010-2024
Title: Innovations of James Zach Hilt
Introduction
James Zach Hilt is a notable inventor based in Lexington, KY (US). He has made significant contributions to the field of drug delivery systems and materials science. With a total of 3 patents, Hilt's work focuses on enhancing therapeutic delivery methods through innovative technologies.
Latest Patents
One of Hilt's latest patents is titled "Delivery systems and methods for reactive hydroxyl-containing compounds." This invention involves the incorporation of curcumin into a hydrolytically degradable crosslinked hydrogel. The hydrogel utilizes poly(beta amino ester) (PBAE) chemistry to create a tunable protective network that releases curcumin at a controlled rate. The results indicate that the microparticle systems improve the amount of curcumin in solution compared to its free state. A kinetic rate model was developed to estimate oxidative consumption parameters of curcumin, enhancing the therapeutic delivery process.
Another significant patent is "Small molecule drug release from in situ forming degradable scaffolds incorporating hydrogels and bioceramic microparticles." This invention presents an injectable system that combines a hydrogel, a bioceramic, and a degradable matrix. It provides sustained drug delivery and structural support to recovering tissues, such as bone and the periodontium.
Career Highlights
Hilt has worked with esteemed institutions, including the University of Kentucky Research Foundation and the University of Texas System. His research has focused on developing advanced materials and systems for medical applications.
Collaborations
Hilt has collaborated with notable colleagues, including Nicholas Peppas and Mark E Byrne. Their combined expertise has contributed to the advancement of innovative drug delivery technologies.
Conclusion
James Zach Hilt's contributions to the field of drug delivery and materials science are noteworthy. His innovative patents and collaborations reflect his commitment to improving therapeutic outcomes through advanced technologies.