Location History:
- Cambridge, MA (US) (2022)
- Newton, MA (US) (2017 - 2023)
Company Filing History:
7 out of 39 
3 out of 3,221 
1 out of 1,153 
Years Active: 2017-2025
Title: Innovations and Contributions of James Xin Sun
Introduction
James Xin Sun is a prominent inventor based in Cambridge, MA, known for his significant contributions to the field of genetic analysis and cancer treatment. With a total of eight patents to his name, he has made remarkable strides in developing methods and systems that enhance our understanding of genetic variants and their implications in cancer.
Latest Patents
One of his latest patents focuses on the analysis of genetic variants. This invention discloses methods and systems for classifying variants in tumor samples as germline, somatic, subclonal, or ambiguous. The classification process involves fitting a genome-wide copy number model to sequence coverage input and SNP allele frequency input. This fitted model aids in determining tumor purity, total copy number, and minor allele copy number for various genomic segments. By utilizing these parameters, the variant can be accurately classified based on its allele frequency in the tumor sample. Another significant patent provides therapeutic and diagnostic methods for cancer, particularly bladder cancer. This invention outlines methods for treating bladder cancer and determining patient responsiveness to treatments involving PD-L1 axis binding antagonists. It also includes methods for selecting appropriate therapies based on somatic mutation levels in tumor samples.
Career Highlights
James Xin Sun has worked with notable companies in the biotechnology sector, including Foundation Medicine, Inc. and Genentech, Inc. His experience in these organizations has contributed to his expertise in genetic research and cancer therapeutics.
Collaborations
Throughout his career, James has collaborated with esteemed colleagues such as Roman Yelensky and David Fabrizio. These partnerships have further enriched his work and expanded the impact of his inventions.
Conclusion
James Xin Sun's innovative work in genetic analysis and cancer treatment exemplifies the vital role of inventors in advancing medical science. His patents not only enhance our understanding of genetic variants but also pave the way for improved therapeutic strategies in cancer care.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.