This inventor holds 1 USPTO granted patent and 4 published patent applications. Top assignee: University of Pittsburgh. Active years: 2019.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2019
Title: Innovations of James Wechuck in Gene Delivery Applications
Introduction
James Wechuck is an accomplished inventor based in Glenshaw, PA (US). He has made significant contributions to the field of gene delivery through his innovative research and patents. His work focuses on developing non-toxic herpes simplex virus (HSV) vectors that enhance the efficiency of gene delivery applications.
Latest Patents
James Wechuck holds a patent for "Non-toxic HSV vectors for efficient gene delivery applications and complementing cells for their production." This invention provides a herpes simplex virus vector that does not express toxic HSV genes in non-complementing cells. The vector comprises a genome that includes one or more transgenes, capable of expressing a transgene for at least 28 days in non-complementing cells. The disclosed vectors feature deletions in the genes ICP0, ICP4, TCP22, TCP27, and TCP47, or alternative inactivating mutations. Additionally, the invention relates to viral stocks of the inventive vectors, therapeutic compositions, and methods for their application. It also provides a complementing cell, specifically a U20S cell, engineered to express ICP4 and ICP27 when infected with HSV for the production of the inventive vector.
Career Highlights
James Wechuck is affiliated with the University of Pittsburgh, where he continues to advance his research in gene delivery systems. His innovative work has garnered attention in the scientific community, contributing to the understanding and application of HSV vectors in therapeutic settings.
Collaborations
James has collaborated with notable colleagues, including Joseph C Glorioso, III, and Darren Wolfe. These partnerships have further enriched his research and expanded the impact of his inventions.
Conclusion
James Wechuck's contributions to the field of gene delivery through his innovative HSV vectors represent a significant advancement in therapeutic applications. His work continues to inspire further research and development in this critical area of biotechnology.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile