James W Yockman

Title: Innovations in Gene Delivery by James W. Yockman

Introduction

James W. Yockman is an accomplished inventor based in Salt Lake City, Utah. He is known for his significant contributions to the field of gene delivery systems. His innovative work focuses on enhancing the delivery of nucleotides through advanced polymer technologies.

Latest Patents

James W. Yockman holds a patent titled "Cleavable modifications to reducible poly(amido ethylenimine)s to enhance nucleotide delivery." This patent discloses improved poly(amido ethylenimine) copolymers designed for gene delivery. One illustrative embodiment includes polyethylene glycol (PEG) covalently bonded to a branched poly(triethyenetetramine/cystamine bisacrylamide) copolymer (poly(TETA/CBA)). The polyethylene glycol can be either linear or branched. Another embodiment features an RGD peptide covalently bonded to the poly(TETA/CBA)-PEG conjugate. Additionally, the patent includes methods for using these compositions to transfect cells with nucleic acids.

Career Highlights

James W. Yockman is affiliated with the University of Utah Research Foundation, where he continues to advance research in gene delivery technologies. His work has garnered attention for its potential applications in medical and biotechnological fields.

Collaborations

James has collaborated with notable colleagues, including Jonathan Brumbach and Lane V. Christensen. Their combined expertise contributes to the innovative research environment at the University of Utah.

Conclusion

James W. Yockman's work in gene delivery represents a significant advancement in the field of biotechnology. His innovative approaches to polymer design and nucleotide delivery have the potential to impact various applications in medicine and research.