Wayne, PA, United States of America

James W Wilson


Average Co-Inventor Count = 2.6

ph-index = 3

Forward Citations = 27(Granted Patents)


Company Filing History:


Years Active: 1976-1986

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5 patents (USPTO):Explore Patents

Title: The Innovations of James W. Wilson

Introduction

James W. Wilson is a notable inventor based in Wayne, Pennsylvania, with a remarkable portfolio of five patents. His work primarily focuses on the development of compounds with significant pharmacological properties, particularly in the field of anti-hypertensive activity.

Latest Patents

One of Wilson's latest patents involves the synthesis of 4-[2-(dialkylamino)ethyl]-7-hydroxyisatins. These compounds are prepared through the internal condensation of an oxime, followed by the removal of protecting groups. The resulting compounds act as D.sub.2-agonists, demonstrating anti-hypertensive activity. A specific example from this group is 4-[2-(di-n-propylamino)ethyl]-4-hydroxyisatin. Additionally, he has developed a potent, selective presynaptic dopaminergic agonist known as N,N-Di-n-propyl-4-hydroxy-3-methanesulfonamidophenethylamine. This compound is synthesized by N-sulfonylation of an optionally O-protected derivative of 3-amino-4-hydroxy-N,N-di-n-propylphenethylamine, followed by the removal of the protecting group.

Career Highlights

Throughout his career, Wilson has made significant contributions to the pharmaceutical industry. He has worked with prominent companies such as SmithKline Beckman Corporation and SmithKline Corporation, where he has applied his expertise in drug development and innovation.

Collaborations

Wilson has collaborated with notable colleagues, including William F. Huffman and Robert M. DeMarinis. Their combined efforts have contributed to advancements in their respective fields and have fostered a collaborative environment for innovation.

Conclusion

James W. Wilson's contributions to the field of pharmacology through his innovative patents and collaborations highlight his significant impact on the industry. His work continues to influence the development of new therapeutic agents.

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