Company Filing History:
5 out of 21 
4 out of 40 
1 out of 136 
Years Active: 1987-1998
Title: Innovations of James W. Schilling, Jr. in Respiratory Medicine
Introduction
James W. Schilling, Jr., hailing from Palo Alto, CA, is a renowned inventor with a significant contribution to the field of respiratory medicine. With a remarkable portfolio of 10 patents, Schilling's innovations focus on the production of recombinant alveolar surfactant proteins, aimed at addressing respiratory deficiency syndromes. His work has had a lasting impact on pharmaceutical compositions and treatments.
Latest Patents
Among Schilling's latest patents are groundbreaking advancements in recombinant alveolar surfactant proteins. These patents disclose recombinant materials for the production of low molecular weight hydrophobic lung surfactant proteins, specifically those with molecular weights of about 5 kd, which form dimers under certain conditions. This collection of recombinant materials enables the production of substantial quantities of these proteins using recombinant techniques, facilitating their application in pharmaceuticals for treating respiratory deficiency syndromes. Furthermore, Schilling's patents reveal the complete coding and amino acid sequences for both canine and human 32K alveolar surfactant proteins (ASP). Included are methods and vectors for obtaining these proteins in recombinant form, as well as innovative purification methods that leverage their carbohydrate affinity. Additionally, pharmaceutical compositions employing both the 10K and 32K proteins, along with synthetic peptides based on human SP-5 protein with significant ASP activity, are part of his impressive portfolio.
Career Highlights
Throughout his career, James W. Schilling, Jr. has worked with notable companies such as California Biotechnology Inc. and Scios Nova, Inc. His expertise in biotechnology and his commitment to innovation have consistently driven advancements in the field.
Collaborations
During his professional journey, Schilling has collaborated with distinguished individuals, including Robert T. White and Barbara Cordell. These partnerships have played a crucial role in enhancing his research and the development of his patented technologies.
Conclusion
James W. Schilling, Jr.'s contributions to the field of respiratory medicine through his extensive patents underscore the importance of innovation in developing effective treatments for respiratory conditions. His work not only highlights his dedication as an inventor but also paves the way for future advancements in the pharmaceutical industry.