James Tumlin

Title: Innovations by James Tumlin in Calcineurin Activity Assessment

Introduction

James Tumlin is an accomplished inventor based in Signal Mountain, TN (US). He has made significant contributions to the field of immunology through his innovative patent that focuses on the assessment of calcineurin activity. His work is particularly relevant for improving therapeutic outcomes in organ transplant recipients.

Latest Patents

James Tumlin holds a patent titled "Methods for determination of calcineurin activity and uses in predicting therapeutic outcomes." This patent describes fluorescence-based assays for measuring calcineurin activity, especially in isolated T cells. The methods involve stimulating T cells with agents that specifically target the T cell receptor (TCR), with or without influencing co-stimulatory pathways. One notable TCR agonist mentioned is monoclonal antibodies specific for CD3. This approach allows for a more precise distinction of calcineurin activity compared to alternative methods, enhancing diagnostic accuracy for individuals undergoing immunosuppressant therapy following organ transplants.

Career Highlights

James Tumlin is affiliated with Emory University, where he continues to advance research in immunology and therapeutic applications. His innovative methods have the potential to significantly impact patient care and treatment strategies in transplant medicine.

Collaborations

James has collaborated with notable colleagues, including Allan D. Kirk and Brian R. Roberts, who share his commitment to advancing medical science and improving patient outcomes.

Conclusion

James Tumlin's contributions to the field of immunology through his patent on calcineurin activity assessment exemplify the importance of innovation in medical research. His work not only enhances diagnostic accuracy but also holds promise for improving therapeutic strategies in organ transplantation.