James T Stivers

Title: Innovations of James T Stivers in HIV Research

Introduction

James T Stivers is an accomplished inventor based in Baltimore, MD (US). He has made significant contributions to the field of molecular biology, particularly in the detection of drug targets related to HIV. His innovative approach has the potential to enhance our understanding of viral interactions and therapeutic interventions.

Latest Patents

Stivers holds a patent for a method titled "Rapid fluorescence detection of binding to nucleic acid drug targets labelled with highly fluorescent nucleotide base analogs." This invention focuses on identifying ligands that interact with cellular processes involved in the life-cycle of HIV. The method involves modifying an oligonucleotide corresponding to a specific RNA sequence within an infected cell by substituting 2-aminopurine. This modification allows for the measurement of interactions between the oligonucleotide and the ligand via fluorescence. The technique can be utilized to discover inhibitors of binding between rev and its response element (RRE), dimerization initiation sequences, and topoisomerases and DNA.

Career Highlights

James T Stivers is associated with the United States of America as represented by the Secretary of the Air Force. His work has been instrumental in advancing research methodologies that can lead to breakthroughs in HIV treatment and prevention.

Collaborations

Some of his notable coworkers include John P Marino and Karen Lacourciere. Their collaborative efforts contribute to the innovative research environment that fosters significant advancements in the field.

Conclusion

James T Stivers exemplifies the spirit of innovation in the scientific community, particularly in the fight against HIV. His patented methods and collaborative work continue to pave the way for future discoveries in molecular biology and therapeutic development.