Location History:
- Swanton, VT (US) (1987)
- Rouses Point, NY (US) (1992)
Company Filing History:
1 out of 1,567 
1 out of 42 Years Active: 1987-1992
Title: James S. Farina: An Innovator in Pharmaceutical Chemistry
Introduction: James S. Farina, an accomplished inventor based in Rouses Point, NY, USA, has made significant contributions to the field of pharmaceutical chemistry. With two patents to his name, Farina has developed innovative processes that enhance the production and efficacy of important pharmaceutical compounds.
Latest Patents: His latest patents include the "Preparation of Propranolol Hydrochloride Macrocrystals" and the "Preparation of 3-Hydroxy-3-Phenylbutan-2-One." The first patent describes a process for producing high yields of propranolol hydrochloride with particle sizes ranging from 420 to 1200 microns. This process utilizes a solvent mixture of n-propanol and heptane, making the macrocrystals suitable for capsule pharmaceutical dosage forms and enabling their use in sustained release formulations. The second patent outlines a method for preparing 3-hydroxy-3-phenylbutan-2-one, which is crucial in the synthesis of acifran. This process involves the reaction of 2,3-butanedione with the appropriate Grignard reagent at low temperatures in tetrahydrofuran or its mixtures with toluene, resulting in high yields.
Career Highlights: Throughout his career, James S. Farina has held positions in notable companies within the pharmaceutical sector, including American Home Products Corporation, where he contributed his expertise in pharmaceutical innovations.
Collaborations: Farina has worked alongside talented professionals such as Paul C. Guley and Corbin L. Cummings. These collaborations have fostered innovation and led to advancements in the development of pharmaceutical processes and products.
Conclusion: James S. Farina's dedication to enhancing pharmaceutical chemistry through innovative processes underscores his role as a significant figure in the industry. His patents reflect a commitment to improving the effectiveness of pharmaceutical products, solidifying his legacy as an inventor and contributor to modern medicine.