Company Filing History:
Years Active: 1996-2000
Title: Innovations of James R. Bischoff
Introduction
James R. Bischoff is a notable inventor based in Kensington, CA (US). He has made significant contributions to the field of viral-based therapies, holding a total of 4 patents. His work focuses on innovative methods for treating neoplastic conditions, showcasing his expertise in biotechnology and medicine.
Latest Patents
Among his latest patents, Bischoff has developed cytopathic adenoviral E1B mutated viruses for therapy and prophylaxis. These methods and compositions are designed to treat neoplastic conditions using viral-based therapy. The mutant virus he has created lacks viral proteins that bind and/or inactivate p53 or RB, allowing it to target neoplastic cells effectively. This selective replication in neoplastic cells leads to preferential killing of these cells, either directly or through the expression of cytotoxic genes. Additionally, he has worked on p53-binding polypeptides and polynucleotides, which have applications in drug development and diagnostics.
Career Highlights
James R. Bischoff has been associated with Onyx Pharmaceuticals, Inc., where he has contributed to groundbreaking research in the field of cancer therapies. His innovative approaches have positioned him as a key figure in the development of viral-based treatments.
Collaborations
Throughout his career, Bischoff has collaborated with talented individuals such as Maria Jose Fernandez-Sarabia and Lelia Wu. These partnerships have enhanced the scope and impact of his research.
Conclusion
James R. Bischoff's work exemplifies the intersection of innovation and medical science. His patents and research continue to pave the way for advancements in cancer treatment, demonstrating the vital role of inventors in improving healthcare outcomes.