Company Filing History:
Years Active: 1999
Title: James P Vaughn: Innovator in Antisense Oligonucleotides
Introduction
James P Vaughn is a notable inventor based in Durham, NC (US). He has made significant contributions to the field of molecular biology, particularly in the development of antisense oligonucleotides. His work focuses on inhibiting the expression of the ERBB2 tyrosine kinase receptor, which has implications for cancer research and treatment.
Latest Patents
James P Vaughn holds a patent for "Antisense oligonucleotides against ERBB-2." This patent includes oligonucleotides consisting of the nucleotide sequences US-3: GGT GCT CAC TGC GGC (SEQ ID NO:2) and UT-1: TGC GGC TCC GGC CCC (SEQ ID NO:5). These oligonucleotides are designed to function as antisense agents, effectively inhibiting the expression of the ERBB2 receptor in both in vitro and in vivo settings.
Career Highlights
Vaughn is affiliated with Duke University, where he continues to advance his research in the field of molecular biology. His work has garnered attention for its potential applications in therapeutic interventions for diseases associated with the ERBB2 receptor.
Collaborations
Some of his notable coworkers include Jeffrey R Marks and James Dirk Inglehart. Their collaborative efforts contribute to the ongoing research and development in the field of cancer biology.
Conclusion
James P Vaughn's innovative work in antisense oligonucleotides represents a significant advancement in molecular biology and cancer research. His contributions continue to influence the scientific community and pave the way for future developments in targeted therapies.