James P Fulginiti

Title: The Innovations of James P. Fulginiti

Introduction

James P. Fulginiti is a notable inventor based in Canandaigua, NY (US). He has made significant contributions to the field of biotechnology, particularly in the development of stable vectors for bacterial hosts. With a total of 2 patents, his work has implications for both fermentation processes and vaccine development.

Latest Patents

Fulginiti's latest patents include innovations related to stable purA vectors. This invention pertains to a complementation system for the selection and maintenance of expressed genes in bacterial hosts. The stable vectors can be selected and maintained by complementation of chromosomal deletion mutations of purA (adenylosuccinate synthetase), eliminating the need for antibiotic resistance genes. This system is particularly useful in production organisms during fermentation and in live vaccine bacteria, such as attenuated Salmonella typhi. It allows for the selection of chromosomal integrants and stable plasmid maintenance in the vaccinated host without the application of external selection pressure.

Career Highlights

Throughout his career, Fulginiti has worked with several prominent companies, including Praxis Biologics, Inc. and American Cyanamid Company. His experience in these organizations has contributed to his expertise in biotechnology and patent development.

Collaborations

Fulginiti has collaborated with notable individuals in his field, including Robert N. Brey, III and Algis Anilionis. These collaborations have likely enriched his work and expanded the impact of his inventions.

Conclusion

James P. Fulginiti's contributions to biotechnology through his patents and collaborations highlight his role as an influential inventor. His work continues to have a lasting impact on the fields of fermentation and vaccine development.