Company Filing History:
Years Active: 1994-1999
Title: Celebrating the Innovations of Inventor James L. Tindall
Introduction
James L. Tindall, an accomplished inventor from Goodwood, CA, has made significant contributions to the field of pharmaceutical chemistry. With a focus on innovative drug formulation processes, Tindall holds a total of two patents that exemplify his expertise and creativity in the industry.
Latest Patents
Tindall's most recent patents highlight his ingenuity in pharmaceutical preparation methods. The first patent pertains to the preparation of Nizatidine, a medication utilized for treating peptic ulcers and gastroesophageal reflux disease. The process involves reacting a specific nitro compound with an aryl or tertiary alkyl sulfonyl halide using a tertiary amine base and a sulfonation catalyst, resulting in the formation of the corresponding sulfonate ester, which is then reacted with dimethylamine to recover Nizatidine.
Another significant patent details the preparation of pure Form 1 Ranitidine hydrochloride. This invention employs a crystallization method from a solution of ranitidine hydrochloride in a mixed solvent. The process integrates a lower alkanol, such as ethanol, with a C6-C10 aromatic hydrocarbon like toluene while utilizing seed crystals of pure Form 1 ranitidine hydrochloride to enhance the crystallization process.
Career Highlights
James L. Tindall is affiliated with Torcan Chemical Ltd., where he has made substantial progress in pharmaceutical innovations. His work not only demonstrates his technical skills but also highlights his commitment to improving therapeutic agents and their formulations.
Collaborations
Throughout his career, Tindall has collaborated with esteemed colleagues, including Teng-Ko Ngooi and Jeffry D. McGolrick. Together, they have contributed to advancing pharmaceutical sciences through their collective expertise and innovative approaches.
Conclusion
James L. Tindall's contributions to the field of pharmaceutical chemistry underscore his role as a prominent inventor. His patents not only reflect his innovative spirit but also pave the way for advancements in drug formulation processes. With a strong foundation of collaboration and a passion for innovation, Tindall continues to influence the landscape of pharmaceutical research and development.