Location History:
- Waban, MA (US) (1997 - 2002)
- Chestnut Hill, MA (US) (2002)
Company Filing History:
9 out of 1,386 
7 out of 2,896 
Years Active: 1997-2002
Title: The Innovations of James L. Michel
Introduction
James L. Michel is a notable inventor based in Waban, Massachusetts, with a significant contribution to the field of medical science. He holds a total of nine patents, showcasing his dedication to innovation and research. His work primarily focuses on vaccines, particularly those aimed at combating infections caused by Group B Streptococcus.
Latest Patents
One of his latest patents is for a Group B Streptococcus vaccine. This invention is designed to protect recipients from infections caused by Group B Streptococcus. The vaccine comprises polysaccharide-protein moieties or protein moieties without a polysaccharide. It can include a group B Streptococcus polysaccharide conjugated to the N-terminal region of the epsilon antigen, a fragment thereof, or their functional derivatives, ensuring the vaccine elicits protective antibodies against the bacteria. The formulation may consist of a single type of polysaccharide-protein unit or a mixture of various types. Additionally, the invention includes a passive vaccine obtained through immunization with either the capsular polysaccharide-protein conjugate or the non-conjugated protein.
Another significant patent is for an immunogenic composition for Group B Streptococcus. This vaccine is also aimed at protecting recipients from infections caused by the bacteria. It provides polysaccharide-protein moieties and contains a group B polysaccharide conjugated to a functional derivative of a group B C protein alpha antigen, which retains the ability to elicit protective antibodies. Similar to his previous patent, this vaccine may contain one type of polysaccharide-protein unit or a mixture of several types.
Career Highlights
Throughout his career, James L. Michel has worked with prestigious institutions, including Brigham and Women's Hospital and General Hospital Corporation. His work in these organizations has allowed him to contribute significantly to medical research and vaccine development.
Collaborations
James has collaborated with esteemed colleagues such as Lawrence C. Madoff and Dennis L. Kasper. These collaborations have further enhanced his research and innovations in the field of vaccines.
Conclusion
James L. Michel's contributions to vaccine development, particularly against Group B Streptococcus, highlight his role as a significant inventor in the medical field. His innovative patents and collaborations reflect his commitment to advancing healthcare solutions.