Location History:
- Boston, MA (US) (2003)
- Weston, MA (US) (2000 - 2005)
Company Filing History:
5 out of 1,370 
1 out of 2,882 
1 out of 1 
Years Active: 2000-2005
Title: Innovations and Contributions of Inventor James K Liao
Introduction
James K Liao is a prominent inventor based in Weston, MA (US), known for his significant contributions to the field of biomedical research. He holds a total of 7 patents, showcasing his innovative approach to solving complex medical challenges. His work primarily focuses on the mechanisms of vascular inflammation and enhancing drug delivery to the brain.
Latest Patents
One of Liao's latest patents addresses the anti-inflammatory actions of cytochrome P450 epoxygenase-derived eicosanoids. His research highlights the role of epoxyeicosatrienoic acids (EETs) in reducing endothelial cell adhesion molecule expression, thereby preventing leukocyte adhesion to the vascular wall. This discovery suggests that EETs play a crucial non-vasodilatory role in managing vascular inflammation.
Another notable patent involves a method for increasing cerebral bioavailability of drugs. Liao's innovative approach involves administering compositions that elevate nitric oxide (NO) levels in the brain, thereby enhancing cerebral blood flow. This method facilitates the delivery of drugs that are typically challenging to introduce into the brain, potentially reducing the serum concentration needed to achieve desired physiological effects.
Career Highlights
Throughout his career, James K Liao has worked with esteemed institutions such as Brigham and Women's Hospital and General Hospital Corporation. His research has significantly advanced the understanding of vascular biology and drug delivery systems, making him a key figure in his field.
Collaborations
Liao has collaborated with notable professionals, including Michael A Moskowitz and Ulrich Laufs, further enriching his research endeavors and expanding the impact of his work.
Conclusion
James K Liao's innovative contributions to biomedical research, particularly in vascular inflammation and drug delivery, underscore his importance as an inventor. His patents reflect a commitment to advancing medical science and improving patient outcomes.
Inventor’s Patent Attorneys refers to legal professionals with specialized expertise in representing inventors throughout the patent process. These attorneys assist inventors in navigating the complexities of patent law, including filing patent applications, conducting patent searches, and protecting intellectual property rights. They play a crucial role in helping inventors secure patents for their innovative creations.