This inventor holds 1 USPTO granted patent. Top assignee: Osiris Therapeutics, Inc.. Active years: 1999.
Company Filing History:
Years Active: 1999
Title: The Innovations of James J Holecek
Introduction
James J Holecek is an accomplished inventor based in Solon, OH (US). He has made significant contributions to the field of biotechnology, particularly in the area of stem cell research. His innovative work has led to the development of a unique composition that supports the viability of human mesenchymal precursor cells.
Latest Patents
James J Holecek holds a patent for a "Chemically defined medium for human mesenchymal stem cells." This invention provides a composition and method for maintaining the viability of human mesenchymal precursor cells in a serum-free environment. The composition includes a minimum essential medium, serum albumin, an iron source, insulin or an insulin-like growth factor, and at least one amino acid selected from glutamine, arginine, and cysteine, while being free of serum. Additionally, it offers a method for culture expanding human mesenchymal precursor cells in a serum-free environment, which further includes a mitogen, particularly a serotonergic agonist. The cells are preferably isolated human mesenchymal stem cells.
Career Highlights
James J Holecek is associated with Osiris Therapeutics, Inc., where he continues to advance his research and innovations. His work has been pivotal in enhancing the understanding and application of stem cell technologies.
Collaborations
One of his notable collaborators is Daniel R Marshak, with whom he has worked closely on various projects related to stem cell research.
Conclusion
James J Holecek's contributions to the field of biotechnology, particularly through his patent on a chemically defined medium for human mesenchymal stem cells, highlight his innovative spirit and dedication to advancing medical science. His work continues to impact the field positively.