Inventors with similar research interests:
Location History:
- Bronx, NY (US) (1979)
- New York, NY (US) (2017)
- Long Beach, NY (US) (2004 - 2021)
- Amesbury, MA (US) (2021 - 2024)
Company Filing History:
42 out of 98 
31 out of 81 
5 out of 31 
Years Active: 1979-2024
Title: The Innovative Mind of James J Donegan: A Leader in Cancer Research and Protein Engineering
Introduction: James J Donegan, based in Long Beach, NY, is a prolific inventor with a remarkable portfolio of 82 patents. His groundbreaking contributions to cancer treatment and protein engineering reflect his deep commitment to scientific research and innovation. Donegan's inventions focus on enhancing therapeutic strategies to combat cancers and related disorders.
Latest Patents: Among Donegan's recent innovations are two notable patents. The first is the development of sphingosine pathway modulating compounds for the treatment of cancers. This invention outlines methods and compositions utilizing sphingosine kinase-1 inhibitors, such as SK1-I, and selective sphingosine-1-phosphate receptor agonists like ozanimod for the effective treatment of cancers and myeloproliferative disorders. The second patent revolves around antibodies specific for sulfation sites of Wnt pathway proteins. It provides compositions that include a protein comprising an antibody binding site targeting sulfated epitopes of Wnt pathway proteins, particularly focusing on the Dickkopf1 (Dkk1) protein.
Career Highlights: Donegan's professional journey includes significant tenure at companies such as Enzo Life Sciences, Inc. and Enzo Biochem, Inc. His work at these organizations has paved the way for numerous advancements in life sciences, particularly in understanding and manipulating cellular pathways associated with cancer.
Collaborations: Throughout his career, Donegan has collaborated with notable professionals in the field, including Elazar S Rabbani and Jannis G Stavrianopoulos. These partnerships have further enriched the research environment, enabling the intersection of diverse ideas and methodologies to foster innovation.
Conclusion: James J Donegan exemplifies the spirit of innovation and dedication to advancing medical science. With 82 patents to his name, his work continues to impact the fields of cancer treatment and protein engineering. His inventions not only reflect his ingenuity but also contribute to the larger goal of improving human health through innovative solutions.
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