Pinole, CA, United States of America

James H Meade


Average Co-Inventor Count = 3.1

ph-index = 2

Forward Citations = 22(Granted Patents)


Company Filing History:


Years Active: 1984-1993

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3 patents (USPTO):Explore Patents

Title: Innovations and Contributions of James H. Meade

Introduction

James H. Meade is a notable inventor based in Pinole, California. He has made significant contributions to the field of biotechnology, particularly in the area of cellulose production and enzyme activity. With a total of 3 patents, his work has had a considerable impact on scientific research and industrial applications.

Latest Patents

James H. Meade's latest patents include innovative methods and nucleic acid sequences for the expression of cellulose. One of his patents discloses nucleic acid sequences encoding the bacterial cellulose synthase operon derived from Acetobacter. This patent describes methods for isolating the genes, vectors containing the genes, and transformed hosts useful for the expression of recombinant bacterial cellulose synthase or production of cellulose. Another significant patent involves a DNA expression vector and its use. This patent details a gene with a DNA sequence complementary to that of the glucoamylase polypeptide mRNA from a fungal species, preferably Aspergillus awamori. The mRNA is an approximately 2.2 kilobase poly A RNA obtained from fungal cells grown under conditions of glucoamylase induction. Reverse transcription of the mRNA provides a glucoamylase probe used to identify genomic digest fragments containing glucoamylase gene regions, which are sequenced to locate the introns and exons. The genomic fragments are spliced together to form a gene that codes for fungal glucoamylase protein and is capable of expressing a non-native protein with glucoamylase enzyme activity upon transformation of a host organism by the vector. The transformed yeast host may be used to produce ethanol.

Career Highlights

James H. Meade has worked at Cetus Corporation, where he has been instrumental in advancing biotechnological innovations. His expertise in genetic engineering and enzyme production has contributed to the development of new methodologies in the field.

Collaborations

Throughout his career, James has collaborated with notable colleagues, including David H. Gelfand and Arie Ben-Bassat. These collaborations have further enhanced the scope and impact of his research.

Conclusion

James H. Meade's contributions to biotechnology through his patents and collaborations have significantly advanced the field. His innovative work continues to influence research and applications in cellulose production and enzyme activity.

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