This inventor holds 1 USPTO granted patent. Top assignee: Bristol-Myers Squibb Compnay. Active years: 1998.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 1998
Title: James Garrett Bradley: Innovator in Epithelial Cell Growth Factors
Introduction
James Garrett Bradley is a notable inventor based in Minnetonka, MN (US). He has made significant contributions to the field of biomedical research, particularly in the area of epithelial cell growth factors. His work has implications for understanding and treating various diseases, including cancer.
Latest Patents
James Garrett Bradley holds a patent for "Fanphiregulins," which is a family of heparin-binding epithelial cell growth factors known as amphiregulins (AR). This invention focuses on the isolation of AR genes from different animal species, the expression of these genes, and the identification of various biologically active AR products. The patent also covers the purification of AR products, the development of antibodies specific for AR, and the potential uses of AR in medical applications. AR is detectable in several normal human epithelial cells and is found in a high percentage of human colon cancers. This invention may accelerate the growth of normal epithelial cells and serve as a growth inhibitor in certain tumor cell lines, particularly breast and ovarian carcinomas. Additionally, AR may function as a growth stimulatory molecule in colorectal carcinomas and could be a useful marker for disease staging and prognosis.
Career Highlights
James Garrett Bradley is associated with Bristol-Myers Squibb Company, where he continues to contribute to innovative research in the pharmaceutical industry. His work has the potential to impact therapeutic strategies for various epithelial-related disorders.
Collaborations
James has collaborated with notable colleagues, including Vicki Lynn McDonald and Mohammed Shoyab, to advance research in his field.
Conclusion
James Garrett Bradley's contributions to the field of epithelial cell growth factors highlight his innovative spirit and dedication to advancing medical science. His patent on amphiregulins represents a significant step forward in understanding and potentially treating various epithelial-related diseases.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile