This inventor holds 1 USPTO granted patent and 1 EPO patent. Top assignee: Carnegie Mellon University. Active years: 2016.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile
Company Filing History:
Years Active: 2016
Title: Innovations of James Fitzpatrick in Fluorescence Detection
Introduction
James Fitzpatrick is an accomplished inventor based in La Jolla, California. He has made significant contributions to the field of fluorescence detection through his innovative designs and patents. His work focuses on enhancing the effectiveness of imaging systems using advanced molecular assemblies.
Latest Patents
Fitzpatrick holds a patent for "Quenched dendrimeric dyes for fluorescence detection." This invention presents designs for high extinction quenched 'dyedrons' that can be activated by converting a single acceptor/quencher in the molecular assembly to a fluorescent state. The quencher is activated by noncovalent binding to a unique complementary expressible fluorogen activating peptide (FAP). This mechanism allows the quencher to act as a homogeneous switch, efficiently receiving energy from each donor molecule of the dendronic antenna and releasing it as fluorescence only when activated by binding. The cumulative effect of the multiple dyes on the antenna results in dramatic enhancements in the effective brightness of the probe in standard imaging systems. This approach provides a set of probes with exceptional brightness, specifically targeted to an expressed tag that activates the fluorescence of the dyedron.
Career Highlights
James Fitzpatrick is affiliated with Carnegie Mellon University, where he continues to advance his research and innovations. His work has garnered attention for its potential applications in various fields, including biomedical imaging and diagnostics.
Collaborations
Fitzpatrick has collaborated with notable colleagues such as Marcel Pierre Bruchez and Lauren A Ernst. Their combined expertise contributes to the advancement of research in fluorescence detection and related technologies.
Conclusion
James Fitzpatrick's innovative work in fluorescence detection exemplifies the impact of advanced molecular designs in scientific research. His contributions continue to enhance imaging systems and open new avenues for exploration in various applications.
Data source: USPTO (United States Patent and Trademark Office) public patent records. Weekly synchronization. How IDiyas builds this profile