Location History:
- South Boston, VA (US) (1989)
- Princeton, NJ (US) (2008 - 2022)
Company Filing History:
14 out of 1,458 
2 out of 3,390 
1 out of 975 
Years Active: 1989-2025
Title: Innovations of James E. Simon: Pioneering Advances in Gene-Edited Plants
Introduction
James E. Simon is a prominent inventor based in Princeton, NJ, recognized for his significant contributions to agricultural biotechnology. With a total of 18 patents to his name, Simon is at the forefront of developing innovative methods and plant varieties that enhance resilience against diseases and unfavorable environmental conditions.
Latest Patents
Among his latest patents, Simon has focused on gene-edited basil plants resistant to downy mildew. The patent outlines methods for creating plants with reduced expression of homoserine kinase (HSK) and 2-oxoglutarate-Fe(II) oxygenase (2OGO), utilizing CRISPR/Cas techniques. These gene-edited plants demonstrate improved resistance to downy mildew and enhanced cold tolerance by reducing the expression of the MYB14 gene. The patent also adds value by providing specific gRNAs and vectors facilitating the gene-editing process.
Another noteworthy innovation by Simon is the catnip cultivar 'CR9.' This invention encompasses seeds and plants of the hybrid catnip 'CR9,' along with methods for producing these plants through crossing with other genotypes, varieties, or cultivars. The versatility of this invention enhances the genetic diversity and potential applications of catnip plants.
Career Highlights
James E. Simon has had an impactful career, particularly at Rutgers, the State University of New Jersey, where he has contributed to research and advancements in plant biotechnology. His dedication to innovation and research has solidified his position as a leader in the field.
Collaborations
Throughout his career, Simon has collaborated with notable colleagues, including William Reichert and Thomas Villani. These partnerships underscore the collaborative nature of research and development in the innovation of new plant varieties and biotechnological advancements.
Conclusion
James E. Simon's work exemplifies the intersection of innovation and agriculture, addressing critical issues such as plant disease resistance and environmental adaptability. His continued efforts in gene editing and hybrid plant development mark significant strides in agricultural science, offering promising solutions for future agricultural sustainability.